Appearance:
Myeloblasts are the first developmental stage of granulopoiesis. Myeloblasts are 15 - 20 µm in diameter; have a basophilic cytoplasm without granules; and a nucleus with fine, slightly structured chromatin and several noticeable nucleoli.
Occurrence:
- Severe bacterial infections with so-called leukemoid reaction.
- Chronic myelocytic leukemia and myelofibrosis with extramedullary hematopoieis.
- Acute myelocytic leukemias.
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